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  1.  
  2. The Upstream Processing chapter of our global biomanufacturing curriculum provides an overview of key elements for operation of a biomanufacturing upstream processing production area, and will help students learn to identify critical process parameters for cell growth and protein production.
  3.  
  4. Production Unit
  5. The fourth unit of our global biomanufacturing curriculum discusses the most important aspects of biomanufacturing.  Under each area you will find our textbook chapter, SOPs, and related curriculum materials.
  6. 1. Upstream Processing
  7. 2. Downstream Processing
  8. 3. Process Development
  9.  
  10. TEXTBOOK CHAPTER
  11. Chapter 10: Upstream Processing
  12.  
  1. BATCH RECORDS
  2. Batch Record: GFP Production from E. coli Upstream Processing
  3. Batch Record: HSA Production from Pichia pastoris Upstream Processing 
  4. Batch Record: tPA Production from CHO Cells Upstream Process
  5.  
  6. SOPs
  7. Applikon Bioreactor Operation SOP
  8. Batch Culture of E. coli Recombinant for Jellyfish Green Fluorescent Protein SOP
  1. Batch Culture of Recombinant tPA Secreting CHO Cells SOP 
  2. Bellco Spinner Flask Cleaning and Autoclaving SOP 
  3. Glucose Determination Assay SOP
  1. Kodak IBI Biolyzer Operation SOP
  2. Labconco Purifier Class 2 Biological Safety Cabinet (BSC) Operation SOP
  3. Lactate Determination Assay SOP
  4. New Brunswick BioFlo 3000 Bioreactor SOP
  5. Operation of Life Technologies Countess II Cell Counter SOP
  6. Process Controlled Fed-Batch Fermentation of Recombinant HSA Secreting Pichia pastoris SOP
  7. Trypan Blue Assay SOP
  1.  
  2. VIRTUAL Labs
  3. Virtual Tour of a Biomanufacturing Facility
  4. By Amgen
  5.  
  6. Virtual Fermentation
  7. By NC Bionetwork

 

  1. GFP biomanufacturing
  2. By NC Bionetwork
  3.  
  4. Biomanufacturing e-Learning Resources
  5. By NC Bionetwork
  6.  
  7. Video
  8. Subculture of a Cell Line (6.5 mins)
  9. By NC Bionetwork
  10.  
  11. Bioprocessing Part 1: Fermentation (15mins)
  12. By NC Bionetwork
  13.  
  14. Skill Standards
  15. Upstream Processing Skill Standards
  16.  
  17. presentations
  18. Technology and Opportunities in Mammalian Cell Culture (56mins)
  19. By Tim Charlebois
  20.  
  21. Humanized Pichia pastoris (46 mins)
  22. By Thomas Potgieter
  23.  
  24. Growing Products in Microalgae: From Nutraceuticals to Human Proteins (56 mins)
  25. By Miguel Oliazola
  26.  
  27. News
  1. Platform Approach Speeds Process Development
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  5. Introduction to Biomanufacturing Master Glossary
introduction,upstream processing,downstream processing
Amgen Virtual Tour of a Biomanufacturing Facility

Take a virtual tour of Amgen's biomanufacturing facilities including their cell culture, recovery and purification, and formulation/distribution...

upstream processing
Antibody Production in Microbial Hosts

 A review of the status of expression of antibodies in microbial hosts and the recent advances in the production of aglycosylated antibodies in...

upstream processing,sop
Applikon Bioreactor Operation SOP

SOP from CHO Cell - tPA Core Production Manual 

sop,upstream processing
Applikon ez-Control Bioreactor Controller Operation

SOP developed by Montgomery County Community College   

sop,upstream processing
Batch Culture of E. coli Recombinant for Jellyfish Green Fluorescent Protein SOP

SOP from Escherichia coli - GFP Core Production Manual 

sop,upstream processing
Batch Culture of Recombinant tPA Secreting CHO Cells

SOP developed by Montgomery County Community College   

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File
Chapter 10 of Introduction to Biomanufacturing 
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File
Production Unit Overview for chapters 10-12 of Introdution to Biomanufacturing 
View File

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