Biomanufacture of Cell and Gene Therapies

Cell-based and gene therapy products are growing and becoming a major component of the biotechnology industry. A recent initiative funded by NIIMBL brought together a collaborative of six partner institutions and their regional CGT industry partners. The goals of the WEBET project, or Workforce Expansion in Biomanufacturing Emerging Technologies, is to reseacrh the workforce needs of the sector,  identify the technical skills and knowledge needed to develop, manufacture, and test these advanced therapies and finally to create hands-on curriculum that will produce well trained graduates ready to join this important biotechnology sector.

On December 3, 2021, and January 24, 2022, InnovATEBio hosted WEBET Train-the-Trainer Webinars- view presentations here:                                                                     

CELL AND GENE THERAPY TRAIN THE TRAINER WEBINAR 1  (Recorded December 3, 2021)  Presentations include: CGT labor market research outcomes, technical skill standards for CGT technicians, course requirements, and newly developed lab-based curriculum on AAV production in HEK 293 cells.                                                             

CELL AND GENE THERAPY TRAIN THE TRAINER WEBINAR 2 ( Recorded January 24, 2022)   Presentations include: Skill Standards and Curriculum for Training Cell and Gene Therapy Technicians, Regulatory Considerations for CGT, CGT Analytics, and newly developed lab-based curriculum on AAV production analytics and AAV transduction evalutation by flow cytometry, immunofluorescence and western blot.

• Presenters and affiliations: 
• Dr. Maggie Bryans Montgomery County Community College
• Professor Jim Dekloe Solano Community College
• Russ Read Forsyth Technical Community College
• Drs. Barbara Juncosa and Dominique Ingato MiraCosta College
• Professor Isso Bayala Quincy College

• Download Labor Market Report Here:

• LABOR MARKET ANALYSIS FOR CELL AND GENE THERAPY TECHNICIAN WORKFORCE

  Prepared for NIIMBL Project 2.2-152  WEBET: Workforce Expansion in Biomanufacturing Emerging Technologies

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• SKILL STANDARDS AND CURRICULUM FOR CELL AND GENE THERAPY TECHNICIANS

  View or Download report here

Upstream and Downstream Processing                                                                                   Coming soon.....

Quality Control                                                                                                                  SOP: viral gene delivery and evaluation using flow cytometry

Equipment Required for Training Cell and Gene Therapy Technicians

AAV Vector Manufacturing: Challenges and Opportunities